Christine D. Keating

This study shows that coacervates protect RNA from hydrolysis during wet-dry cycling with Mg2+ by creating a stable microenvironment, as demonstrated with an unstructured RNA and a ligase ribozyme.

This study creates an artificial multiphase coacervate system that dynamically reorganizes in response to pH, enabling controlled catalytic reactions through phase composition adjustments.

This study shows that using diverse single-chain amphiphiles in hybrid protocell membranes increases stability and structural diversity, enhancing their viability in varying environments.

This study investigates how different crowding agents affect protein phase separation using NMR, revealing residue-level environmental influences and highlighting the importance of crowder identity.

This study investigates how coacervates resist changes in molecular composition under varying salinity and pH, showing they can buffer molecules like RNA and maintain internal stability.

This paper describes hybrid protocells combining coacervate droplets with fatty acid membranes, showing improved stability and functional interior chemistry.

This study creates synthetic cells with membraneless organelles that sequester RNA and modulate protein expression, advancing understanding of natural organelle function and synthetic biology.