Author

Keith A. Young

United States Department of Veterans AffairsORCID 0000-0001-6060-3573Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:gene regulatory network inference· 2 Research Focus:benchmarking· 1 Research Focus:fine-mapping· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

Alanna C. CoteiD· 2 shared Carina SeahiD· 2 shared Emily M. HicksiD· 2 shared John Harrison KrystaliD· 2 shared Kristen BrennandiD· 2 shared Laura M. HuckinsiD· 2 shared Matthew J. GirgentiiD· 2 shared Michael Deans· 2 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersNeuroscience

Alanna C. CoteORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintOct 23, 2024

Decoding the transcriptomic signatures of psychological trauma in human cortex and amygdala

Emily M. Hicks, Carina Seah, Michael Deans…·Laura M. Huckins

The paper investigates transcriptional signatures of trauma in human brain regions using RNA-seq data from 304 donors, identifying differential vulnerability of cortical and amygdala regions to different trauma types.

DOI 10.1101/2024.10.23.619681

humanbulk RNA-seq

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GeneticsbioRxivPreprintDec 27, 2023

Common genetic variation impacts molecular stress response in the brain

Carina Seah, Rebecca H. Signer, Michael Deans…·Laura M. Huckins

The paper identifies stress-interactive eQTLs that dysregulate gene expression in the brain under stress, uncovering novel genes linked to brain disorder risk in traumatic stress contexts.

11 citations

humanbulk RNA-seq

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NeuroscienceAmerican Journal of PsychiatryPeer-reviewedJul 6, 2022

Decoding shared versus divergent transcriptomic signatures across cortico-amygdala circuitry in PTSD and depressive disorders

Andrew E. Jaffe, Ran Tao, Matthew Nguyen Tran…·Joel E. Kleinman

The paper identifies differentially expressed genes in PTSD and MDD across brain regions, highlighting shared and unique transcriptional patterns and immune-related pathways.

59 citationstop 1%

humanbulk RNA-seq

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