Matthew Nguyen Tran

This study identifies KCNT1's role in multiciliated cell development in Xenopus and links it to pharmacologically tractable Piezo channels.

The paper generates a molecular neuroanatomical map of the human prefrontal cortex using spatial transcriptomics and single nucleus RNA-sequencing, revealing novel spatial domains and cell-cell interactions linked to psychiatric disorders.

This study investigates TrkB signaling in the lateral septum using RNA-seq, identifying gene expression changes linked to psychiatric and neurodegenerative disorders.

The paper identifies cell type-specific activity-regulated gene expression patterns in mouse hippocampal neurons using snRNA-seq and ECS, revealing divergent transcriptomic responses and enriched biological pathways.

The paper characterizes the molecular landscape of the human locus coeruleus using spatially-resolved transcriptomics and single-nucleus RNA-sequencing, providing a publicly accessible resource.

The paper identifies differentially expressed genes in PTSD and MDD across brain regions, highlighting shared and unique transcriptional patterns and immune-related pathways.

The paper identifies electrophysiological measures in hiPSC-derived neurons linked to schizophrenia diagnosis and cognitive performance.

The paper uses snRNA-seq to analyze five human brain regions, identifies novel neuronal subpopulations, and links them to psychiatric and substance use risks.

The paper shows that incorporating cell size parameters improves deconvolution of brain RNA-seq data, but using external cell size estimates can introduce bias.

The paper maps spatial gene expression in the human dorsolateral prefrontal cortex using spatial transcriptomics and identifies layer-specific gene expression patterns linked to neuropsychiatric disorders.