Zuyun Liu

methylCIPHER is a local R package providing standardized epigenetic clock calculation, clock-selection helpers, and missing-CpG imputation assessment, showing that many clocks produce highly correlated outputs despite non-overlapping CpGs.

This study identifies genetic associations for two biological age measures, revealing distinct aging phenotypes linked to different pathways and APOE variants.

This study compares 11 epigenetic aging clocks using DNA methylation data from human tissues and cells, finding differences in CpG characteristics, tissue specificity, and gene network associations.