Author
Buck Institute for Research on AgingORCID 0000-0001-6123-1505Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
3 papers
Recent·Most cited
Carlos Galicia Aguirre, Kizito‐Tshitoko Tshilenge, Elena Battistoni…·Lisa Ellerby
The paper uses single-cell RNA sequencing to study Huntington's disease by analyzing medium spiny neuron development in HD iPSC models and identifies potential therapeutic molecules.
Kizito‐Tshitoko Tshilenge, Carlos Galicia Aguirre, Joanna Bons…·Lisa Ellerby
The paper performs proteomic analysis of Huntington's disease patient-derived medium spiny neurons, identifying altered lipid metabolism and lipid droplet accumulation as key findings.
Paula García-Huerta, Paulina Troncoso-Escudero, Di Wu…·Claudio A. Hetz
This study identifies IGF2 as a disease modifier that reduces intracellular protein aggregates by promoting their extracellular disposal in Huntington's disease models.