BioinformaticsClinical EpigeneticsPeer-reviewed
Improving the clinical performance of blood-based DNA methylation biomarkers utilizing locus-specific epigenetic heterogeneity
Brendan Miller, Thomas R. Pisanic, Gennady Margolin…·Laura L. Elnitski
This paper develops EpiClass, a methylation density-based classifier that improves the performance of blood-based DNA methylation biomarkers in detecting ovarian cancer by leveraging locus-specific epigenetic heterogeneity.
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