Author

Christina M. Annunziata

American Cancer SocietyORCID 0000-0003-2033-6532Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Akosua Osei-Tutu· 1 shared Alexander GoncearencoiD· 1 shared Brendan MilleriD· 1 shared Cameron Baker· 1 shared Cameron W. A. SnyderiD· 1 shared Elizabeth A. LaMere· 1 shared Elizabeth Pritchett· 1 shared Gennady Margolin· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBioinformatics

Akosua Osei-Tutu

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMay 5, 2026

IL1β/IL1R1/IRAK4 Drives Inflammatory Ovarian Cancer Seeding at the inflamed sites and Is Reversed by an IRAK4 inhibitor UR241-2

J. Miller, Kyukwang Kim, Cameron W. A. Snyder…·Rakesh K. Singh

This paper identifies the IL1β/IL1R1/IRAK4 axis as critical for inflammation-driven ovarian cancer metastasis and shows that IRAK4 inhibition with UR241-2 reduces tumor seeding and activates antitumor immune responses.

DOI 10.64898/2026.04.30.722105

mouseproteomics

𝕏 PostBluesky

BioinformaticsClinical EpigeneticsPeer-reviewedOct 20, 2020

Improving the clinical performance of blood-based DNA methylation biomarkers utilizing locus-specific epigenetic heterogeneity

Brendan Miller, Thomas R. Pisanic, Gennady Margolin…·Laura L. Elnitski

This paper develops EpiClass, a methylation density-based classifier that improves the performance of blood-based DNA methylation biomarkers in detecting ovarian cancer by leveraging locus-specific epigenetic heterogeneity.

19 citations

humanDNA methylation

𝕏 PostBluesky