Author

Vinay Ayyappan

University of PennsylvaniaORCID 0000-0001-6133-6083Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Developmental Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Arjun RajiD· 2 shared Anthony K. L. LeungiD· 1 shared Calvin Barber· 1 shared Catherine G. TriandafillouiD· 1 shared Christina A. ViveloiD· 1 shared Christos SazeidesiD· 1 shared Garth Cook· 1 shared Kathryn Gauch· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersDevelopmental Biology

Arjun RajORCID

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3 papers

Recent·Most cited

Developmental BiologybioRxivPreprintJul 12, 2025

Gastruloid patterning reflects division of labor among biased stem cell clones

Vinay Ayyappan, Catherine G. Triandafillou, Kavitha Sarma, Arjun Raj

The paper shows that stem cell clones in gastruloids exhibit spatial propensities for anterior/posterior fates, leading to spontaneous division of labor during axial organization.

5 citations

spatial transcriptomicsexperimental assay

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Systems BiologyCell SystemsPeer-reviewedNov 29, 2022

Allelic correlation is a marker of tradeoffs between barriers to transmission of expression variability and signal responsiveness in genetic networks

Ryan H. Boe, Vinay Ayyappan, Lea Schuh, Arjun Raj

The paper develops a mathematical framework to model allelic correlation and noise transmission in genetic networks, finding trade-offs between noise transmission and signal responsiveness.

3 citations

humanscRNA-seq

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BioinformaticsNucleic Acids ResearchPeer-reviewedOct 31, 2020

ADPriboDB v2.0: An Updated Database of ADP-ribosylated Proteins

Vinay Ayyappan, Ricky Wat, Calvin Barber…·Anthony K. L. Leung

ADPriboDB v2.0 updates a database of ADP-ribosylated proteins with 9,097 entries, including 6,708 new proteins, and links ADP-ribosylation to SARS-CoV-2 protein interactions and other post-translational modifications.

52 citations

humanproteomics

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