Author

Saskia Freifrau von Stillfried

Universitätsklinikum AachenORCID 0000-0002-5260-8494Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Peter BooriD· 2 shared Anna Luisa HilleriD· 1 shared Barbara M. KlinkhammeriD· 1 shared Benjamin OndruschkaiD· 1 shared Birgit SawitzkiiD· 1 shared Bruno MärkliD· 1 shared Burcu Yesilyurt Öztürk· 1 shared Christian MeiseliD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersImmunology

Peter BoorORCID

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2 papers

Recent·Most cited

Rewired type I IFN signaling is linked to age-dependent differences in COVID-19

Lev Petrov, Sophia Brumhard, Sebastian Wisniewski, Philipp Georg, David Hillus, Anna Luisa Hiller, Rosario Astaburuaga-García, Nils Blüthgen, Emanuel Wyler, Katrin Vogt, Hannah-Philine Dey, Saskia Freifrau von Stillfried, Christina Iwert, Roman David Bülow, Bruno Märkl, , Birgit Sawitzki

This study identifies age-related rewiring of type I IFN signaling in immune cells linked to increased inflammation and altered antibody responses in COVID-19.

Cell Reports Medicine · Aug 1, 2025Peer-reviewedImmunology

The role of Platelet-derived growth factor (PDGF) in uremic vascular calcification.

Burcu Yesilyurt Öztürk, Li Zhang, Saskia Freifrau von Stillfried, Barbara M. Klinkhammer, Julia Möllmann, Patrick Droste, Eva Miriam Buhl, Mathias Hohl, Heidi Noels, Vera Jankowski, Joachim Jankowski, Claudia Goettsch, Nikolaus Marx, Lorin E. Olson, Jürgen Floege, , Peter Boor

This study investigates the role of PDGFR-{beta} in uremic vascular calcification using ex vivo and in vivo models, showing that PDGFR-{beta} activation promotes calcification and VSMC phenotypic switching.

bioRxiv · Jul 9, 2025 · PreprintSystems Biology