Developmental BiologybioRxivPreprint
Hyaluronic acid dynamics are regulated by neural crest cells and NEDD4 in the developing cardiac outflow tract valves
Jasmine Hartmann, Deepti Domingo, Sarah Boyle…·Sophie Wiszniak
This study shows that NEDD4 in neural crest cells regulates HA synthesis in cardiac outflow tract valves, affecting valve development and ECM composition.
DOI 10.64898/2026.11.08.764443