Author

Sophie Wiszniak

South Australia PathologyORCID 0000-0001-8666-9300Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Markus Tondl· 2 shared Quenten SchwarziD· 2 shared Ceilidh L. MarchantiD· 1 shared Chaya KalcheimiD· 1 shared Congenital Heart Disease Synergy Group· 1 shared David Scott WinlawiD· 1 shared Deepti DomingoiD· 1 shared Dimuthu AlankarageiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersDevelopmental Biology

Markus Tondl

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2 papers

Recent·Most cited

Neural crest cell derived DKK1 modulates Wnt signalling in the second heart field to orchestrate cardiac outflow tract development

Sophie Wiszniak, Dimuthu Alankarage, Iman Lohraseb, Ceilidh L. Marchant, Genevieve A. Secker, Deepti Domingo, Jasmine Hartmann, Tianyang Zhang, Wendy Parker, John Toubia, Melissa A. White, Sandra Piltz, Markus Tondl, Eleni Giannoulatou, David Scott Winlaw, , Quenten Schwarz

The paper identifies DKK1 from neural crest cells as a regulator of Wnt signaling in the second heart field, crucial for cardiac outflow tract development and linked to congenital heart disease.

Nature Communications · Jan 22, 2026Peer-reviewedDevelopmental Biology

Notch signaling is a critical initiator of roof plate formation as revealed by the use of RNA profiling of the dorsal neural tube

Shai Ofek, Sophie Wiszniak, Sarah A. Kagan, Markus Tondl, Quenten Schwarz, Chaya Kalcheim

The paper uses transcriptome analysis to identify genes involved in Notch-dependent roof plate formation and shows Notch signaling is critical for RP development and fate determination.

BMC Biology · Apr 23, 2021Peer-reviewedDevelopmental Biology