Cell BiologyMolecular Biology of the CellPeer-reviewed
Significantly reduced, but balanced, rates of mitochondrial fission and fusion are sufficient to maintain the integrity of yeast mitochondrial DNA
Brett T. Wisniewski, Jason C. Casler, Laura L. Lackner
The paper shows that balanced, reduced rates of mitochondrial fission and fusion maintain mtDNA integrity in yeast, and increased mtDNA copy number reduces respiratory loss in mutants.
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