Author

Aitor Zabala

University of the Basque CountryORCID 0000-0001-6227-7089Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2 Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Research Focus:benchmarking· 2 Assay:bulk RNA-seq· 1 Research Focus:database / resource· 1 Research Focus:eQTL / molecular QTL mapping· 1 Approach:experimental assay· 1 Assay:GWAS summary statistics· 1 Assay:metagenomics· 1

Frequent Co-Authors

David OtaeguiiD· 4 shared Alex M. AscensióniD· 3 shared Iñigo Prada-LuengoiD· 2 shared Anders KroghiD· 1 shared Ane Otaegui-ChiviteiD· 1 shared Eduardo Andrés-LeóniD· 1 shared Frederik Otzen BaggeriD· 1 shared Fuencisla MatesanziD· 1 shared

Activity by Year

2026-2026 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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4 shared papersBioinformatics

David OtaeguiORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

GenomicsbioRxivPreprintOct 21, 2026

Extrachromosomal circular DNA formation follows a 10.5-bp periodicity reflecting the minor groove orientation around nucleosomes

Aitor Zabala, Alex M. Ascensión, Frederik Otzen Bagger…·Iñigo Prada-Luengo

The paper analyzes eccDNA length distributions and breakpoint organization across multiple datasets to show that eccDNA formation is influenced by nucleosome positioning and DNA helix orientation.

DOI 10.64898/2026.10.19.760212

multiple speciesstatistical model

𝕏 PostBluesky

BioinformaticsbioRxivPreprintJun 29, 2026

MBIOME: A comprehensive, reproducible, and open-source workflow for amplicon-based microbiome data analysis.

Miriam Gorostidi-Aicua, Ane Otaegui-Chivite, Aitor Zabala…·David Otaegui

MBIOME provides an open-source workflow for amplicon-based microbiome analysis, validated across sequencing platforms and showing improved flexibility and taxonomic resolution.

DOI 10.64898/2026.06.25.734448

metagenomicsstatistical model

𝕏 PostBluesky

GeneticsbioRxivPreprintJun 1, 2026

Circular RNA-associated QTLs show stronger association with splicing-QTLs than with expression-QTLs

Aitor Zabala, Alex M. Ascensión, Saioa GS Iñiguez…·Maider Muñoz‐Culla

The paper compares circQTLs with splicing and expression QTLs, finding stronger genomic overlap with splicing-QTLs and distinct genomic distribution patterns.

DOI 10.64898/2026.05.29.728707

GWAS summary statisticsstatistical model

𝕏 PostBluesky

BioinformaticsGigaSciencePeer-reviewedJan 1, 2026

Comparative analysis of eccDNA and circRNA tools shows increased accuracy of tool combination

Aitor Zabala, Alex M. Ascensión, Iñigo Prada-Luengo, David Otaegui

The paper evaluates circular nucleic acid detection tools, finding that combining at least three tools improves accuracy.

2 citations

bulk RNA-seqstatistical model

𝕏 PostBluesky