Author
Columbia UniversityORCID 0000-0001-7387-0312Unclaimed ORCID profile · follow to get notified of new preprints
7 papers
Recent·Most cited
Li Wan, Menghan Liu, Panos Oikonomou…·Wenyan Jiang
This study identifies gene-drug and gene-gene interactions in Staphylococcus aureus using CRISPR-interference, revealing vulnerabilities for new drug targets and combination therapies.
Amir Momen-Roknabadi, Panos Oikonomou, Saeed Tavazoie
The paper shows human cells adapt to methotrexate through stochastic tuning, a process similar to yeast, which is reversible and not mutation-driven.
Călin C. Guet, Luke Bruneaux, Panos Oikonomou…·P Cluzel
The paper studies the mar operon in E. coli using single-cell lineage tracking, revealing inducible memory of promoter activity across generations.
Seth R. Taylor, Gabriel Santpere, Alexis Weinreb…·David M. Miller
The paper provides a comprehensive gene expression profile of all 302 neurons in the C. elegans nervous system and identifies cis-regulatory elements and adhesion proteins involved in synaptic specificity.
Amir Momen-Roknabadi, Panos Oikonomou, Maxwell Zegans, Saeed Tavazoie
The paper develops an inducible CRISPRi library for S. cerevisiae to systematically interrogate gene function with high precision and low false discovery rate.
Sydney B. Blattman, Wenyan Jiang, Panos Oikonomou, Saeed Tavazoie
PETRI-seq enables single-cell RNA sequencing of prokaryotes by overcoming technical barriers, revealing growth phase-specific cell states and prophage induction in S. aureus.
Charles E. Vejnar, Mario Abdelmessih, Carter M. Takacs…·Antonio J. Giráldez
The paper identifies cis-regulatory elements and trans-factors governing mRNA stability during zebrafish MZT and develops a model to predict mRNA stability.