Author

Ali Mobasheri

University Medical Center UtrechtORCID 0000-0001-6261-1286Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Organism:mouse· 1 Assay:proteomics· 1 Organism:rat· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Adam Williams· 1 shared Annemarie LangiD· 1 shared Bernadette JeremiasseiD· 1 shared Caroline Amy StauntoniD· 1 shared Christopher R. FellowsiD· 1 shared Csaba MattaiD· 1 shared David AllawayiD· 1 shared Fiona O’BrieniD· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperMolecular Biology

Adam Williams

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3 papers

Recent·Most cited

Molecular BiologyOsteoarthritis and CartilagePeer-reviewedMar 21, 2021

Combining segmental bulk- and single-cell RNA-sequencing to define the chondrocyte gene expression signature in the murine knee joint

Vikram Sunkara, Gitta Anne Heinz, Frederik Heinrich…·Annemarie Lang

This study combines bulk and single-cell RNA-seq to identify chondrocyte gene expression in murine knee joints, finding 75 overlapping genes related to cartilage homeostasis and osteoarthritis.

22 citations

mousebulk RNA-seq

𝕏 PostBluesky

Molecular BiologybioRxivPreprintMay 5, 2020

Clusterin secretion is attenuated by pro-inflammatory cytokines in culture models of cartilage degradation

Csaba Matta, Christopher R. Fellows, Helen L. Quasnichka…·Ali Mobasheri

The paper shows that pro-inflammatory cytokines reduce sCLU secretion and expression in cartilage models, suggesting sCLU as a biomarker for cartilage degradation in OA.

2 citations

proteomicsstatistical model

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BioinformaticsFrontiers in PhysiologyPeer-reviewedMar 24, 2020

Pro-inflammatory cytokines drive deregulation of potassium channel expression in primary synovial fibroblasts

Omar Haidar, Nathanael O’Neill, Caroline Amy Staunton…·Richard Barrett‐Jolley

The paper investigates how TNF and IL1β cytokines affect potassium channel expression in rat synovial fibroblasts, finding increased Kcnma1 and Kcnmb3 gene expression.

15 citations

ratbulk RNA-seq

𝕏 PostBluesky