Combining segmental bulk- and single-cell RNA-sequencing to define the chondrocyte gene expression signature in the murine knee joint
Vikram Sunkara, Gitta Anne Heinz, Frederik Heinrich, Pawel Durek, Ali Mobasheri, Mir‐Farzin Mashreghi, Annemarie Lang
This study combines bulk and single-cell RNA-seq to identify chondrocyte gene expression in murine knee joints, finding 75 overlapping genes related to cartilage homeostasis and osteoarthritis.
Osteoarthritis and Cartilage · Mar 21, 2021Peer-reviewedMolecular Biology