Margaret A. Roy

The paper analyzes genetic diversity in naked mole-rats from Kenya and Ethiopia using whole-genome sequencing and a chromosome-scale genome assembly, revealing unexpected genetic divergence patterns.

The paper investigates age-related changes in muscle progenitors by analyzing single-cell RNA-seq data from young and aged mice, finding that differentiation amplifies age-related changes in progenitors but masks some changes.

Solo identifies doublets in scRNA-seq data using semi-supervised deep learning, improving accuracy over existing methods.

The paper shows that a novel eIF2B activator prevents neurological defects in a mouse model of Vanishing White Matter disease by normalizing the transcriptome and proteome.