Author

Sina B. Kirchhofer

Max Planck Institute for Medical ResearchORCID 0000-0001-6285-9054Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Approach:microscopy & imaging analysis· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Anna-Lena Krett· 1 shared Katharina Klingelhöfer· 1 shared Moritz BünemanniD· 1 shared Volker JelinekiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperPharmacology & Toxicology

Anna-Lena Krett

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1 paper

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintDec 15, 2025

Dissecting GPCR Selectivity: A complex interplay of various intracellular motifs determines G-protein binding and activation

Sina B. Kirchhofer, Volker Jelinek, Katharina Klingelhöfer…·Moritz Bünemann

This study investigates how intracellular motifs in Muscarinic receptors influence G-protein binding and activation, showing that selectivity arises from complex interactions rather than single motifs.

DOI 10.64898/2025.12.12.693856

mouseproteomics

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