Regan L. Scott

This study identifies TFAP2C as a critical regulator of trophoblast cell invasion and hemochorial placentation in rats, showing its role in both early development and later gestation.

This paper develops a conditional rat model to study invasive trophoblast cell lineage regulation and its role in uterine spiral artery remodeling.

The paper compares chromatin accessibility and gene regulatory networks in invasive trophoblast cells between rat and human to identify conserved regulatory mechanisms.

The paper uses genome-edited rat models to show AKT1 and FOXO4 reciprocally regulate hemochorial placenta development.

This study identifies conserved transcriptomic features of invasive trophoblast cells in rat and human placentation, providing insights into shared regulatory mechanisms essential for healthy pregnancy.