Ayelen Moreno‐Irusta

This study identifies PPARG as a critical regulator of trophoblast cell differentiation and uterine-placental interface formation in both human and rat models.

This study identifies TFAP2C as a critical regulator of trophoblast cell invasion and hemochorial placentation in rats, showing its role in both early development and later gestation.

This study shows that NOTUM downregulates WNT signaling to drive EVT cell differentiation from human trophoblast stem cells, essential for placental development and healthy pregnancy.

This study shows that TAF7L is essential for male germ cell development in rats, leading to infertility due to meiotic arrest and failed sperm production.

This paper develops a conditional rat model to study invasive trophoblast cell lineage regulation and its role in uterine spiral artery remodeling.

This study investigates the role of CITED2 in regulating the uterine-placental interface in rat and human models, showing its critical role in trophoblast cell development and placental function.

The paper uses genome-edited rat models to show AKT1 and FOXO4 reciprocally regulate hemochorial placenta development.