Author

Joshua Chan

Elements Biosciences (United States)ORCID 0000-0001-6313-1946Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2 Organism:human· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Adeline Mah· 2 shared Andrew M. BoddickeriD· 2 shared Bryan R. LajoieiD· 2 shared Juan Moreno· 2 shared Junhua ZhaoiD· 2 shared Laure Edoli· 2 shared Peter T. Mains· 2 shared Semyon KruglyakiD· 2 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenomics

Adeline Mah

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2 papers

Recent·Most cited

GenomicsBMC GenomicsPeer-reviewedSep 2, 2025

A simplified hybrid capture approach retains high specificity and enables PCR-free workflow

Adeline Mah, Xiaodong Qi, Junhua Zhao…·Michael J. R. Previte

This paper introduces a simplified hybrid capture method that eliminates PCR and bead-based steps while maintaining specificity and improving variant calling.

5 citations

whole-genome sequencingexperimental assay

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GenomicsNature BiotechnologyPeer-reviewedMay 25, 2023

Sequencing by avidity enables high accuracy with low reagent consumption

Sinan Arslan, Francisco J. Garcia, Minghao Guo…·Jordan M. Neysmith

This paper introduces avidity sequencing, a new chemistry that improves sequencing accuracy and reduces reagent use, enabling applications like single-cell RNA-seq and whole-genome sequencing.

83 citationstop 1%

humanwhole-genome sequencing

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