Thomas Jackson

This study identifies multimorbidity clusters and their genetic architecture but finds no significant genetic overlap with long COVID.

The paper develops a toolkit to measure multiple ageing hallmarks in human blood and tissue samples, identifying age-related changes in immune cells, senescence, and mitochondrial function.

This study finds that frail older adults have impaired macrophage phagocytosis and a less diverse respiratory microbiome, which may be linked to PPARγ pathway dysfunction.

This paper introduces a framework to build saliva-based DNA methylation biomarkers, demonstrating a new epigenetic clock (InflammAge) that quantifies systemic chronic inflammation and outperforms CRP in several health outcomes.