BiochemistryNature CommunicationsPeer-reviewed
A split crRNA with CRISPR-Cas12a enables highly sensitive, selective, and multiplexed detection of RNA and DNA
Yi-Chuan Chen, Xinping Wang, Junqi Zhang…·Yi Liu
This paper develops a split CRISPR-Cas12a system for sensitive, selective, and multiplexed detection of RNA and DNA without reverse transcription, achieving low detection limits and improved specificity.
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