Cancer BiologyMolecular Cancer TherapeuticsPeer-reviewed
A whole genomic CRISPR-Cas9 screen identifies the amino acid transporter SLC43A1 (LAT3) as a major determinant of oxaliplatin sensitivity in colorectal cancer cells
Nisha R. Pawar, HM Wade, Zoè Jackson…·Michael M. Gottesman
The paper identifies SLC43A1 (LAT3) as a key determinant of oxaliplatin sensitivity in colorectal cancer cells through CRISPR screens and functional validation.
DOI 10.1158/1535-7163.mct-25-0508