Author

Jonathan S. Brammeld

Wellcome Sanger InstituteORCID 0000-0001-6355-7680Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Francesco IorioiD· 2 shared Iñigo MartincorenaiD· 2 shared Julio Sáez-RodrígueziD· 2 shared Luz García‐AlonsoiD· 2 shared Ultan McDermottiD· 2 shared Alba Dalmases· 1 shared Beatríz BellosilloiD· 1 shared Carla Daniela Robles‐EspinozaiD· 1 shared

Activity by Year

2017-2018 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioinformatics

Francesco IorioORCID

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2 papers

Recent·Most cited

BioinformaticsScientific ReportsPeer-reviewedApr 24, 2018

Pathway-based dissection of the genomic heterogeneity of cancer hallmarks’ acquisition with SLAPenrich

Francesco Iorio, Luz García‐Alonso, Jonathan S. Brammeld…·Julio Sáez-Rodríguez

The paper develops SLAPenrich to analyze pathway alterations in cancer hallmarks across 4,415 patients, revealing hallmark predominance and suggesting novel driver genes.

32 citations

humanwhole-exome sequencing

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GeneticsGenome ResearchPeer-reviewedApr 1, 2017

Genome-wide chemical mutagenesis screens allow unbiased saturation of the cancer genome and identification of drug resistance mutations.

Jonathan S. Brammeld, Mia Petljak, Iñigo Martincorena…·Ultan McDermott

This paper describes a method to identify drug resistance mutations in cancer using genome-wide chemical mutagenesis and next-generation sequencing, enabling the discovery of both known and novel resistance mechanisms.

23 citations

humanwhole-genome sequencing

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