Yang Mo Gu

This paper demonstrates the de novo biosynthesis of cannabinoids and their analogs in Yarrowia lipolytica through metabolic engineering.

This study improves the biosynthesis of the cannabinoid precursor olivetolic acid in Yarrowia lipolytica by overcoming rate-limiting steps, achieving an 83-fold increase in OLA titer.

This paper engineers Yarrowia lipolytica to produce five aromatic chemicals and natural products by modifying the shikimate pathway and blocking competing pathways.

This paper improves strain stability and pathway yield in engineered yeast by coupling metabolic addiction with negative autoregulation.