Author

Laura S. van Dam

Stanford UniversityORCID 0000-0001-6373-7673Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

Mengrui ZhangiD· 3 shared William H. RobinsoniD· 3 shared Eun Kyung SongiD· 2 shared Jae‐Seung MooniD· 2 shared Melanie H. SmithiD· 2 shared Orr SharpeiD· 2 shared Tobias Volker LanziD· 2 shared Aline BozeciD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersImmunology

Mengrui ZhangORCID

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintNov 2, 2026

CD19-CAR T-cell therapy resets the EBV+ autoreactive B cell repertoire in autoimmune disease

Ya'el Courtney, Mahesh Pandit, Laura S van Dam…·William H Robinson

This study shows CD19-CAR T-cell therapy depletes EBV+ autoreactive B cells and resets their repertoire, leading to sustained remission, while rituximab does not.

DOI 10.64898/2026.10.24.761515

humanbulk RNA-seq

𝕏 PostBluesky

ImmunologybioRxivPreprintJun 8, 2026

Cross-presentation of citrullinated antigens drives cytotoxic CD8+ T cell responses in rheumatoid arthritis

Jae‐Seung Moon, Mengrui Zhang, Laura S. van Dam…·William H. Robinson

The paper identifies a mechanism where TLR4-driven cross-presentation of citrullinated antigens by dendritic cells and autoreactive B cells activates CD8+ T cells in rheumatoid arthritis.

DOI 10.64898/2026.06.03.729882

humanbulk RNA-seq

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ImmunologybioRxivPreprintOct 14, 2025

Senescent Activated Naive B Cells Promote Anti-Citrullinated Antigen T Cell Responses and the Transition to Clinical Rheumatoid Arthritis

Xiaohao Wu, Mengrui Zhang, Jae‐Seung Moon…·William H. Robinson

This study identifies senescent activated naive B cells in ACPA+ individuals that promote anti-citrullinated antigen T cell responses and drive progression to clinical RA.

3 citations

humanscRNA-seq

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