Cell BiologybioRxivPreprint
AMPKγ2 Deacetylation Drives Nuclear Translocation and Doxorubicin-Induced Cardiomyopathy via Nucleolar Stress Signaling
Canrong Li, Tiantian Yi, Y M Cui…·Xiaoduo Xie
This study identifies AMPKγ2 deacetylation as a driver of Doxorubicin-induced cardiomyopathy through nucleolar stress and p53-mediated apoptosis, suggesting HDAC inhibitors could mitigate cardiac toxicity.
DOI 10.64898/2026.07.16.737177