Lukas Hafner

The paper develops ChoruMM, a multi-components mixed model for bacterial GWAS, showing that standard human genetics models are inadequate for highly structured bacterial genomes.

The paper addresses concerns about ChEC-seq's ability to distinguish signal from noise by demonstrating normalization methods and validating its reliability through functional assays.

This study identifies Sfp1 as a master regulator of cell growth and division in yeast by coordinating gene expression through two distinct promoter binding modes.