BioinformaticsJournal of Molecular and Cellular CardiologyPeer-reviewed
Prediction of Kv11.1 potassium channel PAS-domain variants trafficking via machine learning
Kalyan Immadisetty, Xuan Fang, Geraldine San Ramon…·Peter Michael Kekenes-Huskey
This study uses machine learning and molecular dynamics simulations to predict which KCNH2 variants disrupt Kv11.1 channel trafficking, improving variant classification accuracy by ~10%.
5 citations