Kalyan Immadisetty

The paper shows that early arginine methylation of KCa3.1 limits Ca2+-mediated NFAT1 activation, preventing T cell exhaustion during activation.

This study uses molecular dynamics simulations to compare conformational transitions in MFS transporters, finding similar mechanisms across classes with some functional differences.

This study uses machine learning and molecular dynamics simulations to predict which KCNH2 variants disrupt Kv11.1 channel trafficking, improving variant classification accuracy by ~10%.