ImmunologybioRxivPreprint
Structure-guided deimmunisation of Fel d 1 suppresses allergic effector functions ex vivo
Kyungsoo Ha, Soo‐Young Yum, Hyeji Kwon…·Yoonjoo Choi
This study designs hypoallergenic variants of Fel d 1 by disrupting IgE-binding sites, showing reduced IgE reactivity and suppressed basophil activation ex vivo.
DOI 10.64898/2026.03.18.712552