Dan Zhou

This study examines hypoxia's effects on Drosophila embryos by analyzing chromatin accessibility and gene expression, identifying dose-dependent changes and a critical role for the tramtrack gene in germ cell development.

This study shows that FXR deficiency prevents IHC-induced atherosclerosis by disrupting microbiome-bile acid signaling in ApoE-/- mice.

This study uses RNA-sequencing to show that PHOX2B polyalanine repeat mutation significantly alters the transcriptome of neuronal progenitor cells in Haddad syndrome.

This study shows that gut microbiota and their metabolites contribute to OSA-induced atherosclerosis, particularly in the aorta, through specific bacterial imbalances and bile acid dysregulation.

This study shows methadone exposure during early cortical development alters synapse-related transcriptional programs in human cortical organoids.