Chenxu Zhu

The paper constructs an integrative single-cell epigenomic atlas of the adult mouse brain, mapping chromatin states and gene regulatory programs across 100 cell subclasses.

This study examines hypoxia's effects on Drosophila embryos by analyzing chromatin accessibility and gene expression, identifying dose-dependent changes and a critical role for the tramtrack gene in germ cell development.

The paper introduces SeqTag, a single-cell multiomics method, to analyze molecular asynchrony in regulatory layers and model cellular kinetics during aging.

This paper presents a single-cell multiome atlas of the human basal ganglia, linking chromatin states and transcriptomes to cell-type identity and disease-associated variants.

The paper constructs a single-cell chromatin accessibility atlas of the human brain, identifies cell-type-specific regulatory elements, and develops models to predict regulatory function of disease risk variants.

SnapFISH identifies chromatin loops from multiplexed DNA FISH data with high sensitivity and accuracy in mouse embryonic stem cells.

SnapHiC-D identifies differential chromatin contacts between two scHi-C datasets with high sensitivity and accuracy, showing correlation with cell-type-specific gene expression and epigenomic features.

This study identifies BmHen1 as essential for eupyrene sperm development in B. mori, while PIWI proteins Siwi and BmAgo3 are not involved in this process.

This paper introduces ATRAC-seq, a method using Tn5 transposase to tagment RNA/DNA hybrids for RNA sequencing, offering a faster and simpler library construction protocol.