Sayantan Bose

This study identifies Neuropilin 2 (NRP2) as a co-inhibitory receptor that regulates antigen-induced inflammation and allograft rejection by modulating CD4+ T cell responses.

The paper introduces metaVIPER, an algorithm to assess protein activity in orphan tissues and single cells by integrating multiple non-tissue-matched interactomes, improving reproducibility of protein-activity signatures.