Athanasios Zovoilis

This study identifies an m6A epitranscriptomic signature in systemic sclerosis that drives profibrotic changes, which can be reversed by METTL3 inhibition.

The paper identifies a unique circRNA signature in congenital diaphragmatic hernia (CDH) lung development, showing miRNA sponging effects and pathway overlaps between rat and human CDH.

The paper identifies increased A-to-I RNA editing of SINE B2 non-coding RNAs in mouse models of amyloid beta toxicity, linking it to stress-responsive gene expression.

NERD-seq improves detection of non-coding RNAs in direct RNA-seq by expanding representation of previously excluded RNA classes in mouse brain tissue.

The paper shows increased processing of SINE B2 non-coding RNAs in amyloid beta toxicity leads to deregulation of stress response genes and contributes to neuro-pathology.