Luke Saville

This study identifies PAN3-AS1 as an oncogenic lncRNA in AML, shows its role in chromatin organization, and demonstrates RNA-targeting LNP therapy to reduce leukemia burden.

The paper identifies increased A-to-I RNA editing of SINE B2 non-coding RNAs in mouse models of amyloid beta toxicity, linking it to stress-responsive gene expression.

NERD-seq improves detection of non-coding RNAs in direct RNA-seq by expanding representation of previously excluded RNA classes in mouse brain tissue.

This study uses nanopore sequencing to analyze RNA modifications and their correlations with other RNA features in human cells, revealing negative associations and pathway-specific responses.

The paper shows increased processing of SINE B2 non-coding RNAs in amyloid beta toxicity leads to deregulation of stress response genes and contributes to neuro-pathology.