Author

Mark A. Brockman

Simon Fraser UniversityORCID 0000-0001-6432-1426Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Aniqa ShahidiD· 2 shared Chanson J. BrummeiD· 2 shared Evan Barad· 2 shared Winnie W. Y. DongiD· 2 shared Zabrina L. BrummeiD· 2 shared Bradley R. JonesiD· 1 shared Charlotte Johanna BeeleniD· 1 shared Claudia Champagne· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersMicrobiology

Aniqa ShahidORCID

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintNov 5, 2026

HIV-1 Vpu complements HLA-A downregulation by Nef and impairs TCR-mediated recognition of HIV-infected cells through distinct mechanisms

Mariana G Bego, Tram NQ Pham, Claudia Champagne…·Eric A. Cohen

This study shows HIV-1 Vpu reduces HLA-A expression and impairs TCR recognition, acting independently of Nef and requiring BST2/tetherin.

DOI 10.64898/2026.11.04.764327

humanproteomics

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MicrobiologymBioPeer-reviewedMar 30, 2026

Prolonged non-suppressible viremia sustained by a clonally expanded, genomically defective provirus with an immune-evasive HIV protein expression profile

F. Harrison Omondi, Yurou Sang, Winnie W. Y. Dong…·Zabrina L. Brumme

The paper describes a case of prolonged non-suppressible viremia caused by clonally expanded, genomically defective HIV proviruses with immune-evasive protein expression profiles.

2 citationstop 4%

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GeneticsmBioPeer-reviewedNov 16, 2023

HIV reservoirs are dominated by genetically younger and clonally enriched proviruses

Natalie N. Kinloch, Aniqa Shahid, Winnie W. Y. Dong…·Zabrina L. Brumme

This study identifies that HIV reservoirs consist mainly of genetically younger, clonally enriched proviruses from the pre-ART period, with defective proviruses persisting longer.

21 citations

humanDNA methylation

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