Winnie W. Y. Dong

This paper studies HIV superinfection to show how immune responses shape rebound dynamics and reservoir reactivation during treatment interruption.

The paper describes a case of prolonged non-suppressible viremia caused by clonally expanded, genomically defective HIV proviruses with immune-evasive protein expression profiles.

This study identifies that HIV reservoirs consist mainly of genetically younger, clonally enriched proviruses from the pre-ART period, with defective proviruses persisting longer.

This study analyzes HIV proviral diversity and compartmentalization in blood and lung during suppressive ART, finding shared sequences and limited genetic compartmentalization.

This paper evaluates RT-ddPCR primer/probe sets for SARS-CoV-2 RNA quantification, identifies optimal sets, and establishes a method to convert Ct values to RNA copy numbers.

The paper evaluates the Intact Proviral DNA Assay (IPDA) for HIV reservoir quantification, finding that HIV diversity leads to a 28% failure rate and underestimation of reservoir size.