Vidar Martin Steen

This paper identifies potential nootropic drug targets by integrating large-scale cognitive GWAS and transcriptomic data to find credible druggable genes.

The paper investigates the association between predicted brain C4A expression and cognitive performance and brain imaging measures in the UK Biobank, finding significant negative associations and structural mediation effects.

The paper examines if human-specific differentially methylated regions (hDMRs) associated with schizophrenia show methylation differences in brain samples between patients and controls.

The paper compares three variant callers for human whole genome sequencing and finds DeepVariant outperforms others in indel calling.

The paper identifies human-specific methylated regions enriched in schizophrenia GWAS signals and shows their enrichment surpasses other evolutionary markers.

This study performs a large-scale GWAS of cognitive ability, identifies 70 genomic loci, and finds tissue-specific gene expression and potential drug targets.