Author

Fatima Martín‐Sánchez

Manchester Academic Health Science CentreORCID 0000-0001-6447-3358Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

David BroughiD· 1 shared Gloria López‐CastejóniD· 1 shared Siyi Bai· 1 shared

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2024-2024 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperImmunology

David BroughORCID

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1 paper

Recent·Most cited

ImmunologyCell Death DiscoveryPeer-reviewedAug 8, 2024

Pyroptosis leads to loss of centrosomal integrity in macrophages

Siyi Bai, Fatima Martín‐Sánchez, David Brough, Gloria López‐Castejón

This study shows that NLRP3 inflammasome activation in macrophages leads to loss of centrosomal scaffold protein PCNT, affecting centrosome structure and potentially contributing to inflammatory disease pathogenesis.

8 citations

humanmouse

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