Andreas Füglistaler

This study uses ancient genomes of Alpine ibex to show that past population dynamics and genetic diversity loss are critical for understanding current conservation challenges.

SweepLink jointly infers demography and linked selection from time-series data, improving detection of selection signals compared to single-locus methods.

This study reconstructs the genomic history of the extinct giant deer, revealing genetic vulnerabilities linked to its extinction.

This paper develops T-SenSER, a synthetic biosensor for T cells that enhances anti-tumor responses by sensing TME factors like VEGF and CSF1, showing improved efficacy in lung cancer and multiple myeloma models.