Christine Grossen

This study uses ancient genomes of Alpine ibex to show that past population dynamics and genetic diversity loss are critical for understanding current conservation challenges.

The paper develops a workflow using UMAP and t-SNE on genotype likelihoods from low-coverage sequencing to analyze population structure in scimitar-horned oryx.

The paper identifies a recessive lethal allele in reintroduced lynx populations linked to organ mineralization, showing how inbreeding and founder effects drive its frequency increase.

The paper identifies ongoing hybridization between Alpine ibex and domestic goat using SNP analysis and phenotype data, revealing a hybrid swarm in specific regions.

The paper estimates hybridization load in Alpine ibex due to hybridization with domestic goats, finding increased loss-of-function mutations in hybrids compared to non-hybrids.

The paper identifies recent introgression from domestic goats into Alpine ibex genomes, particularly at immune-related loci, suggesting adaptive benefits during population recovery.

The paper presents a chromosome-level genome assembly for the Aldabra giant tortoise and uses it to analyze population structure and genetic origins.

The paper develops a targeted amplicon sequencing assay to genotype immune-related loci in Alpine ibex, showing it can resolve population structure as effectively as other methods with less data.