Author

Toni Giorgino A

National Research CouncilORCID 0000-0001-6449-0596Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Genetic & Genomic Medicine· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:GWAS / association mapping· 2 Organism:human· 2 Approach:experimental assay· 1 Assay:GWAS summary statistics· 1

Frequent Co-Authors

A. Forman· 2 shared A. Fritsche· 2 shared Adem Y. DawediD· 2 shared Amelie Bonneford· 2 shared Andrea MariiD· 2 shared Angus G. JonesiD· 2 shared Anita M. HennigeiD· 2 shared Anubha MahajaniD· 2 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

A. Forman

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3 papers

Recent·Most cited

BiophysicsbioRxivPreprintOct 22, 2026

Calcium-Driven Activation of Gelsolin: Mechanism and the Active-State Ensemble

Bruno Stegani, Loic Girois, Federico Ballabio…·Matteo de Rosa

This study elucidates the mechanism of gelsolin activation through a combination of experimental and computational methods, revealing a dynamic, domain-dependent process leading to a heterogeneous active-state ensemble.

DOI 10.64898/2026.10.16.759396

experimental assaystatistical model

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Genetic & Genomic MedicineThe Lancet Diabetes & EndocrinologyPeer-reviewedDec 15, 2022

Pharmacogenomics of GLP-1 Receptor Agonists: A genome-wide analysis of observational data and large randomized controlled trials

Adem Y. Dawed, Andrea Mari, Andrew Anand Brown…·A. Jonsson

This study identifies genetic variants associated with glycaemic response to GLP-1 receptor agonists using observational and trial data, finding variants in GLP-1R and ARRB1 linked to HbA1c reduction.

137 citationstop 1%

humanGWAS summary statistics

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GeneticsDiabetes CarePeer-reviewedMar 18, 2019

Variation in the plasma membrane monoamine transporter (PMAT, encoded in SLC29A4) and organic cation transporter 1 (OCT1, encoded in SLC22A1) and gastrointestinal intolerance to metformin in type 2 diabetes: an IMI DIRECT study

Adem Y. Dawed, Kaixin Zhou, Nienke van Leeuwen…·A. Forman

This study investigates the association between genetic variants in PMAT and OCT1 transporters and metformin gastrointestinal intolerance in type 2 diabetes patients.

72 citationstop 2%

humanstatistical model

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