Author

Leslie G. Smith

Oregon Health & Science UniversityORCID 0000-0001-6452-6624Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 3

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 3 Research Focus:gene regulatory network inference· 3 Organism:human· 3 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:proteomics· 1

Frequent Co-Authors

Mathew J. ThayeriD· 3 shared Michael B. HeskettiD· 3 shared Paul T. SpellmaniD· 3 shared Phillip A. YatesiD· 2 shared Athanasios E Vouzas· 1 shared Christopher T. BonifaceiD· 1 shared David M. GilbertiD· 1 shared Eric E. BouhassiraiD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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3 shared papersGenetics

Mathew J. ThayerORCID

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3 papers

Recent·Most cited

GeneticseLifePeer-reviewedMar 11, 2024

ASAR lncRNAs control DNA replication timing through interactions with multiple hnRNP/RNA binding proteins

Mathew J. Thayer, Michael B. Heskett, Leslie G. Smith…·Phillip A. Yates

The paper identifies ASAR lncRNAs as regulators of DNA replication timing through interactions with hnRNP proteins, showing their role in chromosome stability and replication synchronization.

5 citations

humanDNA methylation

𝕏 PostBluesky

GeneticsbioRxivPreprintApr 25, 2022

Epigenetic Control of Hundreds of Chromosome-Associated lncRNA Genes Essential for Replication and Stability

Michael B. Heskett, Athanasios E Vouzas, Leslie G. Smith…·Mathew J. Thayer

The paper identifies hundreds of epigenetically controlled long noncoding RNA genes essential for chromosome replication and stability, validating their role in chromosomal integrity.

DOI 10.1101/2022.04.25.489405

humanDNA methylation

𝕏 PostBluesky

GeneticsRNAPeer-reviewedMar 6, 2020

Reciprocal monoallelic expression of ASAR lncRNA genes controls replication timing of human chromosome 6.

Michael B. Heskett, Leslie G. Smith, Paul T. Spellman, Mathew J. Thayer

The paper identifies a new lncRNA gene, ASAR6-141, that regulates replication timing of human chromosome 6 through reciprocal monoallelic expression and inactivation/stability centers.

36 citations

humanDNA methylation

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