Author

John W. Ribis

Tufts University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Assay:DNA methylation· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Aimee SheniD· 2 shared Gang FangiD· 2 shared Alex Kim· 1 shared Ali BashiriD· 1 shared Andrew KasarskisiD· 1 shared Aneel K. Aggarwal· 1 shared Camille Hamula· 1 shared Colleen Beckford· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMicrobiology

Aimee ShenORCID

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2 papers

Recent·Most cited

A single DNA methylation site regulates cell fate during Clostridioides difficile sporulation.

Pola Kuhn, John W. Ribis, Mi Ni, Gang Fang, Aimee Shen

The paper identifies a single DNA methylation site that regulates sporulation in C. difficile by enhancing spoIIE transcription and sigmaF activation, revealing its role in pathogen persistence and potential as an antimicrobial target.

PLoS Pathogens · Jul 23, 2026Peer-reviewedMicrobiology

Epigenomic and functional characterization of a core DNA methyltransferase in the human pathogen Clostridium difficile

Pedro H. Oliveira, John W. Ribis, Elizabeth M. Garrett, Dominika Trzilova, Alex Kim, Ognjen Sekulović, Edward A. Mead, Theodore Pak, Shijia Zhu, Gintaras Deikus, Marie Touchon, Colleen Beckford, Nathalie E. Zeitouni, Deena Altman, Elizabeth Webster, , Gang Fang

This study characterizes the epigenome of C. difficile and identifies a conserved DNA methyltransferase that impacts sporulation and other biological processes.

bioRxiv · Jul 23, 2019 · PreprintGenomics