Stéphanie Mangenot

This study shows septins create size-dependent diffusion barriers on synthetic membranes by organizing into filaments, restricting the movement of membrane-bound objects with large cytosolic domains.

The paper investigates how budding yeast septin filaments affect the mechanical properties of giant unilamellar vesicles (GUVs), finding that large GUVs become more deformable while small ones become less deformable due to septin-induced membrane reshaping.

This study introduces a pipeline using interferometric light microscopy to analyze extracellular vesicles in viscous media, characterizing their transport and the local viscosity of complex fluids.