Author

Isabel Machín-Díaz

Achucarro Basque Center for NeuroscienceORCID 0000-0001-6483-5726Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 4

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Diego ClementeiD· 3 shared María Cristina OrtegaiD· 3 shared Celia Camacho-ToledanoiD· 2 shared Fernando de CastroiD· 2 shared Jennifer García-ArochaiD· 2 shared Rafael Lebrón‐GalániD· 2 shared Alberto ParadelaiD· 1 shared Alberto Pérez‐SamartíniD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersNeuroscience

Diego ClementeORCID

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4 papers

Recent·Most cited

NeuroscienceNeurobiology of DiseasePeer-reviewedApr 17, 2025

Circulating Myeloid-Derived Suppressor Cell load and disease severity are associated to an enhanced oligodendroglial production in a murine model of multiple sclerosis

Mari Paz Serrano‐Regal, Celia Camacho-Toledano, Inmaculada Alonso-García…·Diego Clemente

The paper shows that disease severity in a murine MS model correlates with oligodendrocyte production and that M-MDSCs are associated with increased oligodendrocyte generation.

2 citations

mousebulk RNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintAug 23, 2024

TAF1-dependent transcriptional dysregulation underlies multiple sclerosis

Claudia Rodríguez-López, Ivó H. Hernández, José Terrón-Bautista…·José J. Lucas

This study identifies TAF1-dependent transcriptional dysregulation as a mechanism underlying multiple sclerosis progression and presents an in vivo model for therapeutic development.

DOI 10.1101/2024.08.23.609325

humanbulk RNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintApr 20, 2022

Myeloid-Derived Suppressor Cells are relevant factors to predict the severity of multiple sclerosis

María Cristina Ortega, Rafael Lebrón‐Galán, Isabel Machín-Díaz…·Diego Clemente

The paper identifies myeloid-derived suppressor cells (M-MDSCs) as biomarkers for predicting milder clinical courses in multiple sclerosis.

1 citation

human

𝕏 PostBluesky

NeurosciencebioRxivPreprintOct 11, 2019

Age-linked heterogeneity among oligodendrocyte precursor cells in the cerebral cortex of mice and human

Ana Bribián, Eva Maria Medina-Rodriguez, Fernando Josa‐Prado…·Fernando de Castro

This study examines age-related differences in oligodendrocyte precursor cells (OPCs) from mice and humans, showing distinct metabolic patterns and responses to FGF2 and anosmin-1 across developmental stages.

2 citations

mousehuman

𝕏 PostBluesky