Author

Yitzhak Zimmer

University of BernORCID 0000-0001-6506-8821Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Hugo Guillen-RamireziD· 2 shared Michaela MedováiD· 2 shared Núria Bosch-GuiterasiD· 2 shared Roberta EspositoiD· 2 shared Rory JohnsoniD· 2 shared Tina Uroda· 2 shared Adrian F. OchsenbeiniD· 1 shared Adrienne VancuraiD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenomics

Hugo Guillen-RamirezORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

GenomicsNature CommunicationsPeer-reviewedJun 8, 2023

Tumour mutations in long noncoding RNAs enhance cell fitness

Roberta Esposito, Andrés Lanzós, Tina Uroda…·Rory Johnson

The paper identifies mutated long noncoding RNAs (lncRNAs) as contributors to tumour cell fitness through experimental validation of their oncogenic effects.

22 citations

humanwhole-exome sequencing

𝕏 PostBluesky

Molecular BiologybioRxivFeb 12, 2020

Enhancing CRISPR deletion via pharmacological delay of DNA-PK

Núria Bosch-Guiteras, Tina Uroda, Hugo Guillen-Ramirez…·Rory Johnson

This paper shows that temporarily inhibiting DNA-PK increases CRISPR-Cas9 deletion efficiency by delaying NHEJ, improving experimental outcomes across multiple cell lines and guide RNAs.

13 citations

humanCRISPR screen

𝕏 PostBluesky