Author

Tina Uroda

University College Dublin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Genomics· 2 Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 4 Approach:experimental assay· 3 Assay:CRISPR screen· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Rory JohnsoniD· 4 shared Hugo Guillen-RamireziD· 3 shared Carlos Pulido-QuetglasiD· 2 shared Michaela MedováiD· 2 shared Michela CoaniD· 2 shared Núria Bosch-GuiterasiD· 2 shared Roberta EspositoiD· 2 shared Sunandini Ramnarayanan· 2 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersGenomics

Rory JohnsonORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Organisational principles of long non-coding RNAs revealed by exon deletion

Sarang Bhutada, Hugo Guillen-Ramirez, Tina Uroda, Ines Jover Bravo, Michela Coan, Antonio Hermoso, Artem Baranovskii, Annalisa Marsico, Rory Johnson

This study uses CRISPR-Cas9 to identify functional exons in lncRNAs, finding most exons are non-functional and functionality is enriched at the 5' end.

bioRxiv · Jun 19, 2026 · PreprintGenomics

Robust CRISPR Screens Identify TPL1 as a Novel Long Noncoding RNA Driving Triple-Negative Breast Cancer Hallmarks

Ramesh Elango, Sunandini Ramnarayanan, Radhakrishnan Vishnubalaji, Lütfiye Yıldız Özer, Michela Coan, Yifan Yu, Sunkyu Choi, Tina Uroda, Carlos Pulido-Quetglas, Frank Schmidt, Khalid Ouararhni, Ayman Al Haj Zen, Rory Johnson, Nehad M. Alajez

The paper identifies TPL1 as a novel long noncoding RNA that drives triple-negative breast cancer hallmarks through multiple molecular mechanisms.

bioRxiv · Aug 6, 2025 · PreprintCancer Biology

Tumour mutations in long noncoding RNAs enhance cell fitness

Roberta Esposito, Andrés Lanzós, Tina Uroda, Sunandini Ramnarayanan, Isabel Büchi, Taisia Polidori, Hugo Guillen-Ramirez, Ante Mihaljevic, Bernard Mefi Merlin, Lia Mela, Eugenio Zoni, Lusine Hovhannisyan, Finn McCluggage, Matúš Medo, Giulia Basile, , Rory Johnson

The paper identifies mutated long noncoding RNAs (lncRNAs) as contributors to tumour cell fitness through experimental validation of their oncogenic effects.

Nature Communications · Jun 8, 2023Peer-reviewedGenomics

Enhancing CRISPR deletion via pharmacological delay of DNA-PK

Núria Bosch-Guiteras, Tina Uroda, Hugo Guillen-Ramirez, Rahel Riedo, Amiq Gazdhar, Roberta Esposito, Carlos Pulido-Quetglas, Yitzhak Zimmer, Michaela Medová, Rory Johnson

This paper shows that temporarily inhibiting DNA-PK increases CRISPR-Cas9 deletion efficiency by delaying NHEJ, improving experimental outcomes across multiple cell lines and guide RNAs.

bioRxiv · Feb 12, 2020Molecular Biology